human ALG8 shRNA silencing AAV

Name
AAV-h-ALG8-shRNA

Cat No
shAAV-200781

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ALG8.

shAAV-200781

AAV-h-ALG8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ALG8 (ALG8, alpha-1,3-glucosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDG1H

Description (Vector)

ALG8 encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

79053

Gene Name (Vector)

ALG8, alpha-1,3-glucosyltransferase

Gene Symbol

ALG8

HGNC ID

HGNC:23161

ORF Size (aa)

1581

ORF Size (bp)

1581 bp

RefSeq ID

NM_024079

RefSeq Synonyms

NM_024079, NM_001007027, BC001133,

Species

human

UniGene ID

Hs.503368

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.