human ALDH1A2 shRNA silencing AAV

Cat. No: shAAV-200726

Availability: 4-5 weeks

Name: AAV-h-ALDH1A2-shRNA

This is an AAV expressing shRNA for silencing of Human ALDH1A2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ALDH1A2
Gene Name: aldehyde dehydrogenase 1 family member A2
Gene ID: 8854
Gene Synonyms: RALDH(II); RALDH2; RALDH2-T
ORF Size: 1443 bp
RefSeq#: NM_170697
Gene Description: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
UniGene ID: Hs.643455
HGNC ID: HGNC:15472