human AKR1D1 shRNA silencing AAV

Name 
AAV-h-AKR1D1-shRNA
Cat No 
shAAV-200692
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AKR1D1.

shAAV-200692
AAV-h-AKR1D1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AKR1D1 (aldo-keto reductase family 1 member D1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3o5bred; CBAS2; SRD5B1
Description (Vector)
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Gene ID
6718
Gene Name (Vector)
aldo-keto reductase family 1 member D1
Gene Symbol
AKR1D1
HGNC ID
HGNC:388
ORF Size (aa)
981
RefSeq ID
NM_005989
RefSeq Synonyms
NM_005989, NM_001190907, NM_001190906, BC130627, BC130625,
Species
human
UniGene ID
Hs.201667

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.