human AICDA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AICDA.
shAAV-200616
AAV-h-AICDA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AICDA (activation induced cytidine deaminase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AID; ARP2; CDA2; HEL-S-284; HIGM2
Description (Vector)
AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Gene ID
57379
Gene Name (Vector)
activation induced cytidine deaminase
Gene Symbol
AICDA
HGNC ID
HGNC:13203
ORF Size (aa)
597
ORF Size (bp)
597 bp
RefSeq ID
NM_020661
RefSeq Synonyms
NM_020661, NM_001330343, BC006296,
Species
human
UniGene ID
Hs.149342
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.