human AGA shRNA silencing AAV

Name
AAV-h-AGA-shRNA

Cat No
shAAV-200541

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AGA.

shAAV-200541

AAV-h-AGA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AGA (aspartylglucosaminidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AGU; ASRG; GA

Description (Vector)

Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified.

Gene ID

175

Gene Name (Vector)

aspartylglucosaminidase

Gene Symbol

AGA

HGNC ID

HGNC:318

ORF Size (aa)

1041

ORF Size (bp)

1041 bp

RefSeq ID

NM_000027

RefSeq Synonyms

NM_001171988, NM_000027, BC012392,

Species

human

UniGene ID

Hs.207776

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.