human ADORA3 shRNA silencing AAV

Name
AAV-h-ADORA3-shRNA

Cat No
shAAV-200491

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ADORA3.

shAAV-200491

AAV-h-ADORA3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADORA3 (adenosine A3 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A3AR

Description (Vector)

ADORA3 encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

140

Gene Name (Vector)

adenosine A3 receptor

Gene Symbol

ADORA3

HGNC ID

HGNC:268

ORF Size (aa)

627

ORF Size (bp)

627 bp

RefSeq ID

NM_000677

RefSeq Synonyms

NM_001302679, NM_001302678, NM_000677, BC064411, BC041707, BC029831,

Species

human

UniGene ID

Hs.281342

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.