human ADIPOR1 shRNA silencing AAV

Name
AAV-h-ADIPOR1-shRNA

Cat No
shAAV-200474

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ADIPOR1.

shAAV-200474

AAV-h-ADIPOR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADIPOR1 (adiponectin receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACDCR1; CGI-45; CGI45; PAQR1; TESBP1A

Description (Vector)

ADIPOR1 encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14.

Gene ID

51094

Gene Name (Vector)

adiponectin receptor 1

Gene Symbol

ADIPOR1

HGNC ID

HGNC:24040

ORF Size (aa)

1128

ORF Size (bp)

1128 bp

RefSeq ID

NM_015999

RefSeq Synonyms

NM_015999, NM_001290629, NM_001290557, NM_001290553, NM_001127687, BC010743, BC001594,

Species

human

UniGene ID

Hs.5298

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.