human ADH7 shRNA silencing AAV

Name 
AAV-h-ADH7-shRNA
Cat No 
shAAV-200463
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ADH7.

shAAV-200463
AAV-h-ADH7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADH4
Description (Vector)
ADH7 encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants.
Gene ID
131
Gene Name (Vector)
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Gene Symbol
ADH7
HGNC ID
HGNC:256
ORF Size (aa)
1161
ORF Size (bp)
1161 bp
RefSeq ID
NM_000673
RefSeq Synonyms
NM_001166504, NM_000673, BC131512,
Species
human
UniGene ID
Hs.389

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.