human ADCY5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ADCY5.
shAAV-200428
AAV-h-ADCY5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ADCY5 (adenylate cyclase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AC5; FDFM
Description (Vector)
ADCY5 encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Gene ID
111
Gene Name (Vector)
adenylate cyclase 5
Gene Symbol
ADCY5
HGNC ID
HGNC:236
ORF Size (aa)
3783
ORF Size (bp)
3783 bp
RefSeq ID
NM_183357
RefSeq Synonyms
NM_183357, NM_001199642, BC156217,
Species
human
UniGene ID
Hs.655144
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.