human ADCY2 shRNA silencing AAV

Name
AAV-h-ADCY2-shRNA

Cat No
shAAV-200423

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ADCY2.

shAAV-200423

AAV-h-ADCY2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADCY2 (adenylate cyclase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AC2; HBAC2

Description (Vector)

ADCY2 encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Gene ID

108

Gene Name (Vector)

adenylate cyclase 2

Gene Symbol

ADCY2

HGNC ID

HGNC:233

ORF Size (aa)

3276

ORF Size (bp)

3276 bp

RefSeq ID

NM_020546

RefSeq Synonyms

NM_020546, BC111743,

Species

human

UniGene ID

Hs.481545

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.