human ACOX2 shRNA silencing AAV

Name
AAV-h-ACOX2-shRNA

Cat No
shAAV-200221

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ACOX2.

shAAV-200221

AAV-h-ACOX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACOX2 (acyl-CoA oxidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BCOX; BRCACOX; BRCOX; THCCox

Description (Vector)

The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children.

Gene ID

8309

Gene Name (Vector)

acyl-CoA oxidase 2

Gene Symbol

ACOX2

HGNC ID

HGNC:120

ORF Size (aa)

2046

ORF Size (bp)

2046 bp

RefSeq ID

NM_003500

RefSeq Synonyms

NM_003500, BC047700,

Species

human

UniGene ID

Hs.444959

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.