human ACER2 shRNA silencing AAV

Cat. No: shAAV-200187

Availability: 6-8 weeks

Name: AAV-h-ACER2-shRNA

This is an AAV expressing shRNA for silencing of Human ACER2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ACER2
Gene Name: alkaline ceramidase 2
Gene ID: 340485
Gene Synonyms: ALKCDase2; ASAH3L
ORF Size: 681 bp
RefSeq#: NM_001010887
Gene Description: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 (PubMed 16940153)).(supplied by OMIM, Jul 2010)
UniGene ID: Hs.41379
HGNC ID: HGNC:23675