human ACAN shRNA silencing AAV

Name 
AAV-h-ACAN-shRNA
Cat No 
shAAV-200162
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ACAN.

shAAV-200162
AAV-h-ACAN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACAN (aggrecan). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK
Description (Vector)
ACAN is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
Gene ID
176
Gene Name (Vector)
aggrecan
Gene Symbol
ACAN
HGNC ID
HGNC:319
ORF Size (aa)
7422
ORF Size (bp)
7422 bp
RefSeq ID
NM_001135
RefSeq Synonyms
NM_013227, NM_001135, BC150624,
Species
human
UniGene ID
Hs.711491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.