human ABT1 shRNA silencing AAV

Name 
AAV-h-ABT1-shRNA
Cat No 
shAAV-200139
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ABT1.

shAAV-200139
AAV-h-ABT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABT1 (activator of basal transcription 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
activator of basal transcription 1; basal transcriptional activator; Esf2; hABT1; TATA-binding protein-binding protein
Description (eCommerce)
Studies in mouse suggest that activator of basal transcription 1 (ABT1) likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA [taken from NCBI Entrez Gene (Gene ID: 55787)].
Description (Vector)
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.
Gene ID
29777
Gene Name (eCommerce)
activator of basal transcription 1
Gene Name (Vector)
activator of basal transcription 1
Gene Symbol
ABT1
HGNC ID
HGNC:17369
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
819
ORF Size (bp)
819 bp
Protein Name (eCommerce)
Activator of basal transcription 1
RefSeq ID
NM_013375
RefSeq Synonyms
NM_013375, BC066313, BC048812,
Research Areas
Neurobiology,Neurodevelopment,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,transcription_translation
Species
human
Target Sentence
Studies in mouse suggest that activator of basal transcription 1 (ABT1) likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA [taken from NCBI Entrez Gene (Gene ID: 55787)].
UniGene ID
Hs.254406
UniProt ID (eCommerce)
Q9ULW3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.