human ABR shRNA silencing AAV

Name
AAV-h-ABR-shRNA

Cat No
shAAV-200136

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ABR.

shAAV-200136

AAV-h-ABR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABR (active BCR-related). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MDB

Description (Vector)

ABR encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.

Gene ID

Gene Name (Vector)

active BCR-related

Gene Symbol

ABR

HGNC ID

HGNC:81

ORF Size (aa)

2580

ORF Size (bp)

2580 bp

RefSeq ID

NM_001092

RefSeq Synonyms

NM_021962, NM_001322842, NM_001322841, NM_001322840, NM_001282149, NM_001256847, NM_001159746, NM_001092, BC172517, BC156483,

Species

human

UniGene ID

Hs.159306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.