human ABCG4 shRNA silencing AAV

Name
AAV-h-ABCG4-shRNA

Cat No
shAAV-200100

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ABCG4.

shAAV-200100

AAV-h-ABCG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCG4 (ATP binding cassette subfamily G member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

WHITE2

Description (Vector)

ABCG4 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.

Gene ID

64137

Gene Name (Vector)

ATP binding cassette subfamily G member 4

Gene Symbol

ABCG4

HGNC ID

HGNC:13884

ORF Size (aa)

1941

ORF Size (bp)

1941 bp

RefSeq ID

NM_022169

RefSeq Synonyms

NM_022169, NM_001142505, BC041091,

Species

human

UniGene ID

Hs.126378

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.