rat RGD1309804 Adenovirus
This is an Adenovirus expressing Rat Rnls.
ADV-292314
Ad-r-RGD1309804
Ready-to-use Adenovirus expressing Rat Rnls (renalase, FAD-dependent amine oxidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1309804
Description (Vector)
Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis (By similarity). According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity.
Gene ID
361751
Gene Name (Vector)
renalase, FAD-dependent amine oxidase
Gene Symbol
Rnls
ORF Size (aa)
948
RefSeq ID
NM_001014167
RefSeq Synonyms
NM_001014167, BC085833,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.