rat VRK1 Adenovirus

Name 
Ad-r-VRK1
Cat No 
ADV-291298
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Anapc2.

ADV-291298
Ad-r-VRK1

Ready-to-use Adenovirus expressing Rat Vrk1 (vaccinia related kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.
Gene ID
362779
Gene Name (Vector)
vaccinia related kinase 1
Gene Symbol
Vrk1
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_001012194
RefSeq Synonyms
NM_001012194, BC079130,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.