rat RAN Adenovirus

Name 
Ad-r-RAN
Cat No 
ADV-290057
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Fam228b.

ADV-290057
Ad-r-RAN

Ready-to-use Adenovirus expressing Rat Ran (RAN, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2|Function: Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Gene ID
84509
Gene Name (Vector)
RAN, member RAS oncogene family
Gene Symbol
Ran
ORF Size (aa)
651
ORF Size (bp)
651 bp
RefSeq ID
NM_053439
RefSeq Synonyms
NM_053439, BC059123,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.