mouse SYNCRIP Adenovirus

Name
Ad-m-SYNCRIP

Cat No
ADV-281139

Availability
4-5 weeks

This is an Adenovirus expressing Mouse 9530053A07Rik.

ADV-281139

Ad-m-SYNCRIP

Ready-to-use Adenovirus expressing Mouse Syncrip (synaptotagmin binding, cytoplasmic RNA interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

2610109K23Rik; 4632417O19Rik; GRY-RBP; hnRNP Q; Nsap1; Nsap1l; pp68

Description (Vector)

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.

Gene ID

56403

Gene Name (Vector)

synaptotagmin binding, cytoplasmic RNA interacting protein

Gene Symbol

Syncrip

ORF Size (aa)

1689

ORF Size (bp)

1689 bp

RefSeq ID

NM_019796

RefSeq Synonyms

NM_019796, NM_019666, NM_001311113, NM_001284328, BC108363, BC080309, BC050079, BC041148,

Species

mouse

UniGene ID

Mm.260545

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.