mouse RNF139 Adenovirus
This is an Adenovirus expressing Mouse Brf1.
ADV-281056
Ad-m-RNF139
Ready-to-use Adenovirus expressing Mouse Rnf139 (ring finger protein 139). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930555P18Rik
Description (Vector)
E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
Gene ID
75841
Gene Name (Vector)
ring finger protein 139
Gene Symbol
Rnf139
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_175226
RefSeq Synonyms
NM_175226, BC052901,
Species
mouse
UniGene ID
Mm.460627
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.