mouse ZIC1 Adenovirus

Name 
Ad-m-ZIC1
Cat No 
ADV-277062
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Zic1.

ADV-277062
Ad-m-ZIC1

Ready-to-use Adenovirus expressing Mouse Zic1 (zinc finger protein of the cerebellum 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ZIC; ZNF201
Description (Vector)
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).
Gene ID
22771
Gene Name (Vector)
zinc finger protein of the cerebellum 1
Gene Symbol
Zic1
ORF Size (aa)
1344
ORF Size (bp)
1344 bp
RefSeq ID
NM_009573
RefSeq Synonyms
NM_009573, BC063247, BC060247, BC050889,
Species
mouse
UniGene ID
Mm.477226

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.