mouse UFD1L Adenovirus

Name
Ad-m-UFD1L

Cat No
ADV-275580

Availability
4-5 weeks

This is an Adenovirus expressing Human LINS1.

ADV-275580

Ad-m-UFD1L

Ready-to-use Adenovirus expressing Mouse Ufd1l (ubiquitin fusion degradation 1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Ufd1

Description (Vector)

Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.

Gene ID

22230

Gene Name (Vector)

ubiquitin fusion degradation 1 like

Gene Symbol

Ufd1l

ORF Size (aa)

924

ORF Size (bp)

924 bp

RefSeq ID

NM_011672

RefSeq Synonyms

NM_011672, BC006630,

Species

mouse

UniGene ID

Mm.237594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.