mouse TMEM66 Adenovirus

Name
Ad-m-TMEM66

Cat No
ADV-274589

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Saraf.

ADV-274589

Ad-m-TMEM66

Ready-to-use Adenovirus expressing Mouse Saraf (store-operated calcium entry-associated regulatory factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1810045K07Rik; Tmem66

Description (Vector)

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

Gene ID

67887

Gene Name (Vector)

store-operated calcium entry-associated regulatory factor

Gene Symbol

Saraf

ORF Size (aa)

1092

ORF Size (bp)

1092 bp

RefSeq ID

NM_026432

RefSeq Synonyms

NM_026432, BC024888, BC022616, BC013497,

Species

mouse

UniGene ID

Mm.290353

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.