mouse THOC3 Adenovirus
This is an Adenovirus expressing Mouse Thoc3.
ADV-274163
Ad-m-THOC3
Ready-to-use Adenovirus expressing Mouse Thoc3 (THO complex 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410044K02Rik; AL033344
Description (Vector)
Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex.The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.
Gene ID
73666
Gene Name (Vector)
THO complex 3
Gene Symbol
Thoc3
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_028597
RefSeq Synonyms
NM_028597, BC019603,
Species
mouse
UniGene ID
Mm.292487
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.