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mouse TELO2 Adenovirus

Name 
Ad-m-TELO2
Cat No 
ADV-274031
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Telo2.

ADV-274031
Ad-m-TELO2

Ready-to-use Adenovirus expressing Mouse Telo2 (telomere maintenance 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1200003M09Rik; AI415602; mKIAA0683; Tel2
Description (Vector)
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Gene ID
71718
Gene Name (Vector)
telomere maintenance 2
Gene Symbol
Telo2
ORF Size (aa)
2523
ORF Size (bp)
2523 bp
RefSeq ID
NM_027880
RefSeq Synonyms
NM_027880, NM_001163661, BC011077,
Species
mouse
UniGene ID
Mm.288702

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.