mouse SRGAP2 Adenovirus
This is an Adenovirus expressing Mouse Srgap2.
ADV-273133
Ad-m-SRGAP2
Ready-to-use Adenovirus expressing Mouse Srgap2 (SLIT-ROBO Rho GTPase activating protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9930124L22Rik; AI448945; FBP2; Fnbp2; srGAP3
Description (Vector)
RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
Gene ID
14270
Gene Name (Vector)
SLIT-ROBO Rho GTPase activating protein 2
Gene Symbol
Srgap2
ORF Size (aa)
3291
ORF Size (bp)
3291 bp
RefSeq ID
NM_001081011
RefSeq Synonyms
NM_001081011, BC172152, BC158055, BC156692, BC152935, BC151082, BC151081,
Species
mouse
UniGene ID
Mm.476747
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.