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mouse SIGMAR1 Adenovirus

Name 
Ad-m-SIGMAR1
Cat No 
ADV-271989
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Sigmar1.

ADV-271989
Ad-m-SIGMAR1

Ready-to-use Adenovirus expressing Mouse Sigmar1 (sigma non-opioid intracellular receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Oprs1; Sig1R; sigma1R
Description (Vector)
Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
Gene ID
18391
Gene Name (Vector)
sigma non-opioid intracellular receptor 1
Gene Symbol
Sigmar1
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_011014
RefSeq Synonyms
NM_011014, NM_001286605, NM_001286551, NM_001286542, NM_001286541, NM_001286540, NM_001286539, NM_001286538, BC019930, BC002000,
Species
mouse
UniGene ID
Mm.425181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.