mouse SHH Adenovirus
This is an Adenovirus expressing Mouse Shh.
ADV-271947
Ad-m-SHH
Ready-to-use Adenovirus expressing Mouse Shh (sonic hedgehog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9530036O11Rik; Dsh; Hhg1; Hx; Hxl3; M100081
Description (Vector)
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).
Gene ID
20423
Gene Name (Vector)
sonic hedgehog
Gene Symbol
Shh
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_009170
RefSeq Synonyms
NM_009170, BC063087,
Species
mouse
UniGene ID
Mm.57202
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.