mouse SCRIB Adenovirus
This is an Adenovirus expressing Mouse Scrib.
ADV-271470
Ad-m-SCRIB
Ready-to-use Adenovirus expressing Mouse Scrib (scribbled planar cell polarity). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI118201; Crc; CRIB; mKIAA0147; Scrb1; SCRIB1; vartul
Description (Vector)
Scaffold protein involved in different aspects of polarized cells differentiation regulating epithelial and neuronal morphogenesis. Most probably functions in the establishment of apico-basal cell polarity. May function in cell proliferation regulating progression from G1 to S phase and as a positive regulator of apoptosis for instance during acinar morphogenesis of the mammary epithelium. May also function in cell migration and adhesion and hence regulate cell invasion through MAPK signaling. May play a role in exocytosis and in the targeting synaptic vesicles to synapses. Functions as an activator of Rac GTPase activity.
Gene ID
105782
Gene Name (Vector)
scribbled planar cell polarity
Gene Symbol
Scrib
ORF Size (aa)
4839
ORF Size (bp)
4839 bp
RefSeq ID
NM_134089
RefSeq Synonyms
NM_134089, NM_001310543, NM_001310542, BC062888, BC060689,
Species
mouse
UniGene ID
Mm.25568
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.