mouse RBL2 Adenovirus
This is an Adenovirus expressing Mouse Rbl2.
ADV-270223
Ad-m-RBL2
Ready-to-use Adenovirus expressing Mouse Rbl2 (retinoblastoma-like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p130; PRB2; Rb2; RBR-2
Description (Vector)
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Gene ID
19651
Gene Name (Vector)
retinoblastoma-like 2
Gene Symbol
Rbl2
ORF Size (aa)
3408
ORF Size (bp)
3408 bp
RefSeq ID
NM_011250
RefSeq Synonyms
NM_011250, NM_001282001, NM_001282000, BC020528,
Species
mouse
UniGene ID
Mm.235580
Recently Viewed Products
Ad-m-RPL23A-shRNA
Cat No: shADV-250073
AAV-r-SOD2
Cat No: AAV-290654
AAV-EF1a-rno-mir-181c-eGFP
Cat No: AAV-MI0000924
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.