mouse MAPT Adenovirus

Name
Ad-m-MAPT

Cat No
ADV-264247

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Mapt.

ADV-264247

Ad-m-MAPT

Ready-to-use Adenovirus expressing Mouse Mapt (microtubule-associated protein tau). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI413597; AW045860; Mtapt; Tau

Description (Vector)

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Gene ID

17762

Gene Name (Vector)

microtubule-associated protein tau

Gene Symbol

Mapt

ORF Size (aa)

1119

ORF Size (bp)

1119 bp

RefSeq ID

NM_010838

RefSeq Synonyms

NM_010838, NM_001285456, NM_001285455, NM_001285454, NM_001038609, BC014748,

Species

mouse

UniGene ID

Mm.449812

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.