mouse KNG1 Adenovirus
This is an Adenovirus expressing Mouse KNG1.
ADV-263034
Ad-m-KNG1
Ready-to-use Adenovirus expressing Mouse Kng1 (kininogen 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Kng
Description (Vector)
(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Gene ID
16644
Gene Name (Vector)
kininogen 1
Gene Symbol
Kng1
ORF Size (aa)
1986
ORF Size (bp)
1986 bp
RefSeq ID
NM_023125
RefSeq Synonyms
NM_023125, NM_001102412, NM_001102411, BC108936, BC018158,
Species
mouse
UniGene ID
Mm.2160
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.