mouse IPO5 Adenovirus
This is an Adenovirus expressing Mouse Ipo5.
ADV-262321
Ad-m-IPO5
Ready-to-use Adenovirus expressing Mouse Ipo5 (importin 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110011C18Rik; 5730478E03Rik; AA409333; C76941; IMB3; Kpnb3; Ranbp5
Description (Vector)
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.
Gene ID
70572
Gene Name (Vector)
importin 5
Gene Symbol
Ipo5
ORF Size (aa)
3294
ORF Size (bp)
3294 bp
RefSeq ID
NM_023579
RefSeq Synonyms
NM_023579, BC054814, BC052392,
Species
mouse
UniGene ID
Mm.472208
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.