mouse GLIS2 Adenovirus
This is an Adenovirus expressing Mouse GLIS2.
ADV-260182
Ad-m-GLIS2
Ready-to-use Adenovirus expressing Mouse Glis2 (GLIS family zinc finger 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gli5; Klf16; Nkl
Description (Vector)
Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).
Gene ID
83396
Gene Name (Vector)
GLIS family zinc finger 2
Gene Symbol
Glis2
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_031184
RefSeq Synonyms
NM_031184, BC021517,
Species
mouse
UniGene ID
Mm.134072
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.