mouse FOXA2 Adenovirus
This is an Adenovirus expressing Human RPP14.
ADV-259551
Ad-m-FOXA2
Ready-to-use Adenovirus expressing Mouse Foxa2 (forkhead box A2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Hnf-3b; HNF3-beta; Hnf3b; HNF3beta; Tcf-3b; Tcf3b
Description (Vector)
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
Gene ID
15376
Gene Name (Vector)
forkhead box A2
Gene Symbol
Foxa2
ORF Size (aa)
1380
ORF Size (bp)
1380 bp
RefSeq ID
NM_010446
RefSeq Synonyms
NM_010446, NM_001291067, NM_001291065, BC160375,
Species
mouse
UniGene ID
Mm.938
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.