mouse EZH1 Adenovirus

Name 
Ad-m-EZH1
Cat No 
ADV-258821
Availability
4-5 weeks

This is an Adenovirus expressing Human RIF1.

ADV-258821
Ad-m-EZH1

Ready-to-use Adenovirus expressing Mouse Ezh1 (enhancer of zeste 1 polycomb repressive complex 2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ENX-2
Description (Vector)
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Gene ID
14055
Gene Name (Vector)
enhancer of zeste 1 polycomb repressive complex 2 subunit
Gene Symbol
Ezh1
ORF Size (aa)
2253
ORF Size (bp)
2253 bp
RefSeq ID
NM_007970
RefSeq Synonyms
NM_007970, BC007135,
Species
mouse
UniGene ID
Mm.5027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.