mouse EBI3 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-257712
Availability:
3-5 weeks
Name:
Ad-m-EBI3
This is an Adenovirus expressing Mouse Ebi3.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ebi3
- Gene Name
- Epstein-Barr virus induced gene 3
- Gene ID
- 50498
- Gene Synonyms
- EBI-3; IL-27
- ORF Size
- 687 bp
- RefSeq#
- BC008209
- Gene Description
- Cytokine with pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
- UniGene ID
- Mm.256798
Related Products
Product | Cat No. |
---|---|
AAV-h-EBI3 | AAV-207516 |
AAV-m-EBI3 | AAV-257712 |
Ad-h-EBI3 | ADV-207516 |
AAV-h-EBI3-shRNA | shAAV-207516 |
AAV-m-EBI3-shRNA | shAAV-257712 |
Ad-h-EBI3-shRNA | shADV-207516 |
Ad-m-EBI3-shRNA | shADV-257712 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy