mouse E2F6 Adenovirus
This is an Adenovirus expressing Mouse E2F6.
ADV-257657
Ad-m-E2F6
Ready-to-use Adenovirus expressing Mouse E2f6 (E2F transcription factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI462434; E2F6a; E2F6b; EMA
Description (Vector)
Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
Gene ID
50496
Gene Name (Vector)
E2F transcription factor 6
Gene Symbol
E2f6
ORF Size (aa)
819
ORF Size (bp)
819 bp
RefSeq ID
NM_033270
RefSeq Synonyms
NM_033270, BC057929, BC037656, BC019166,
Species
mouse
UniGene ID
Mm.23296
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.