mouse DPP4 Adenovirus
This is an Adenovirus expressing Mouse Dpp4.
ADV-257420
Ad-m-DPP4
Ready-to-use Adenovirus expressing Mouse Dpp4 (dipeptidylpeptidase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cd26; Dpp-4; THAM
Description (Vector)
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Gene ID
13482
Gene Name (Vector)
dipeptidylpeptidase 4
Gene Symbol
Dpp4
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_010074
RefSeq Synonyms
NM_010074, NM_001159543, BC022183,
Species
mouse
UniGene ID
Mm.1151
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.