mouse DPH1 Adenovirus

Name 
Ad-m-DPH1
Cat No 
ADV-257409
Availability
4-5 weeks

This is an Adenovirus expressing Mouse DPH1.

ADV-257409
Ad-m-DPH1

Ready-to-use Adenovirus expressing Mouse Dph1 (diphthamide biosynthesis 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1
Description (Vector)
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity).
Gene ID
116905
Gene Name (Vector)
diphthamide biosynthesis 1
Gene Symbol
Dph1
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_144491
RefSeq Synonyms
NM_144491, BC152729,
Species
mouse
UniGene ID
Mm.41496

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.