mouse CRTC1 Adenovirus

Name
Ad-m-CRTC1

Cat No
ADV-256152

Availability
4-5 weeks

This is an Adenovirus expressing Mouse CRTC1.

ADV-256152

Ad-m-CRTC1

Ready-to-use Adenovirus expressing Mouse Crtc1 (CREB regulated transcription coactivator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI413414; Mect1; mKIAA0616; R74955; TORC1

Description (Vector)

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity).

Gene ID

382056

Gene Name (Vector)

CREB regulated transcription coactivator 1

Gene Symbol

Crtc1

ORF Size (aa)

1893

ORF Size (bp)

1893 bp

RefSeq ID

NM_001004062

RefSeq Synonyms

NM_001004062, BC080308,

Species

mouse

UniGene ID

Mm.227767

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.