mouse COL4A2 Adenovirus

Name 
Ad-m-COL4A2
Cat No 
ADV-255857
Availability
4-5 weeks

This is an Adenovirus expressing Human PPP2R3A.

ADV-255857
Ad-m-COL4A2

Ready-to-use Adenovirus expressing Mouse Col4a2 (collagen, type IV, alpha 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Col4a-2
Description (Vector)
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen|Function: Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
Gene ID
12827
Gene Name (Vector)
collagen, type IV, alpha 2
Gene Symbol
Col4a2
ORF Size (aa)
5124
ORF Size (bp)
5124 bp
RefSeq ID
NM_009932
RefSeq Synonyms
NM_009932, BC138040,
Species
mouse
UniGene ID
Mm.181021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.