mouse CFLAR Adenovirus
This is an Adenovirus expressing Mouse Cflar.
ADV-255341
Ad-m-CFLAR
Ready-to-use Adenovirus expressing Mouse Cflar (CASP8 and FADD-like apoptosis regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310024N18Rik; A430105C05Rik; c-Flip; Cash; Casper; CLARP; ENSMUSG00000072980; FLAME; FLAME-1; Flip; Gm9845; I-FLICE; MRIT
Description (Vector)
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Gene ID
12633
Gene Name (Vector)
CASP8 and FADD-like apoptosis regulator
Gene Symbol
Cflar
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_009805
RefSeq Synonyms
NM_207653, NM_009805, NM_001293805, NM_001293804, NM_001289704, BC029223,
Species
mouse
UniGene ID
Mm.336848
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.