mouse AGAP2 Adenovirus
This is an Adenovirus expressing Mouse Agap2.
ADV-252218
Ad-m-AGAP2
Ready-to-use Adenovirus expressing Mouse Agap2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGAP-2; Centg1; cnt-g1; mKIAA0167; PIKE
Description (Vector)
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
Gene ID
216439
Gene Name (Vector)
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Gene Symbol
Agap2
ORF Size (aa)
3561
ORF Size (bp)
3561 bp
RefSeq ID
NM_001033263
RefSeq Synonyms
NM_001301014, NM_001033263, BC156808,
Species
mouse
UniGene ID
Mm.336761
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.