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mouse ACMSD Adenovirus

Name 
Ad-m-ACMSD
Cat No 
ADV-251912
Availability
4-5 weeks

This is an Adenovirus expressing Mouse ACMSD.

ADV-251912
Ad-m-ACMSD

Ready-to-use Adenovirus expressing Mouse Acmsd (amino carboxymuconate semialdehyde decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
Gene ID
266645
Gene Name (Vector)
amino carboxymuconate semialdehyde decarboxylase
Gene Symbol
Acmsd
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
RefSeq ID
NM_001033041
RefSeq Synonyms
NM_001033041, BC139281,
Species
mouse
UniGene ID
Mm.25735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.