human RASGRF1 Adenovirus
This is an Adenovirus expressing Human RASGRF1.
ADV-232049
Ad-h-RASGRF1
Ready-to-use Adenovirus expressing Human RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1
Description (Vector)
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
5923
Gene Name (Vector)
Ras protein specific guanine nucleotide releasing factor 1
Gene Symbol
RASGRF1
HGNC ID
HGNC:9875
ORF Size (aa)
3546
ORF Size (bp)
3546 bp
RefSeq ID
NM_002891
RefSeq Synonyms
NM_153815, NM_002891, NM_001145648, BC040275,
Species
human
UniGene ID
Hs.459035
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.