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human SMARCC2 Adenovirus

Name 
Ad-h-SMARCC2
Cat No 
ADV-231856
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SMARCC2.

ADV-231856
Ad-h-SMARCC2

Ready-to-use Adenovirus expressing Human SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAF170; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein
Description (eCommerce)
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SMARCC2/BAF170 associates with SMARCA2/Brm and SMARCA4/Brg BAF complex and in cooperation with SMARCC1/BAF155, enhances chromatin remodeling activity.
Description (Vector)
SMARCC2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6601
Gene Name (eCommerce)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Gene Name (Vector)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Gene Symbol
SMARCC2
HGNC ID
HGNC:11105
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3645
ORF Size (bp)
3645 bp
Protein Name (eCommerce)
SWI/SNF complex subunit SMARCC2
RefSeq ID
NM_003075
RefSeq Synonyms
NM_139067, NM_003075, NM_001330288, NM_001130420, BC026222, BC013045,
Research Areas
Cancer,Chromatin Remodeling,Neurobiology,Neurodevelopment,Neurogenesis,Nuclear Receptor Coactivators,Prostate Cancer,Signal Transduction,TNF Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,transcription_translation,neurobiology,developmental_biology,cell_biology,signal_transduction,genetics,transcription_translation
Species
human
Target Sentence
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SMARCC2/BAF170 associates with SMARCA2/Brm and SMARCA4/Brg BAF complex and in cooperation with SMARCC1/BAF155, enhances chromatin remodeling activity.
UniGene ID
Hs.236030
UniProt ID (eCommerce)
Q8TAQ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.