human UGT1A10 Adenovirus

Name
Ad-h-UGT1A10

Cat No
ADV-231251

Availability
4-5 weeks

This is an Adenovirus expressing Human UGT1A10.

ADV-231251

Ad-h-UGT1A10

Ready-to-use Adenovirus expressing Human UGT1A10 (UDP glucuronosyltransferase family 1 member A10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

UDPGT; UGT-1J; UGT1-10; UGT1.10; UGT1J

Description (Vector)

UGT1A10 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A10 is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

Gene ID

54575

Gene Name (Vector)

UDP glucuronosyltransferase family 1 member A10

Gene Symbol

UGT1A10

HGNC ID

HGNC:12531

ORF Size (aa)

1326

ORF Size (bp)

1326 bp

RefSeq ID

NM_019075

RefSeq Synonyms

NM_019075, BC069210, BC053576, BC020971,

Species

human

UniGene ID

Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.