human NAIP Adenovirus
This is an Adenovirus expressing Human NAIP.
ADV-231081
Ad-h-NAIP
Ready-to-use Adenovirus expressing Human NAIP (NLR family apoptosis inhibitory protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BIRC1; NLRB1; psiNAIP
Description (Vector)
NAIP is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
4671
Gene Name (Vector)
NLR family apoptosis inhibitory protein
Gene Symbol
NAIP
HGNC ID
HGNC:7634
ORF Size (aa)
4212
ORF Size (bp)
4212 bp
RefSeq ID
NM_004536
RefSeq Synonyms
NM_022892, NM_004536, NM_001346870, BC143761, BC136273,
Species
human
UniGene ID
Hs.654500
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.